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sodium oxybate and pentobarbital each raise sedation. Stay away from or Use Alternate Drug. Restrict use to people for whom alternate remedy alternatives are insufficient
pentobarbital will reduce the level or influence of irinotecan liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the level or outcome of rolapitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Prolonged-expression coadministration of robust CYP3A4 inducers with rolapitant may possibly substantially lower rolapitant efficacy.
pentobarbital will reduce the extent or effect of estradiol vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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pentobarbital will lower the extent or result of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
All drugs may well lead to Uncomfortable side effects. Nevertheless, Lots of individuals haven't any Unwanted effects or only have minimal Unwanted effects. Connect with your medical doctor or get clinical enable if any of those Unwanted effects or some other Unintended effects bother you or do not go away:
pentobarbital will lessen read more the extent or outcome of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Advisable atogepant dosage with concomitant use of robust or moderate CYP3A4 inducers is thirty mg or sixty mg qDay.
pentobarbital will minimize the level or outcome of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the extent or result of tolterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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pentobarbital will lower the level or result of armodafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.
The excretion of unmetabolized barbiturate is one characteristic that distinguishes the very long-performing classification from Individuals belonging to other groups which can be almost totally metabolized. The inactive metabolites of your barbiturates are excreted as conjugates of glucuronic acid.